Abstract: The four stages for the discipline construction of China safety science are reviewed. It is proposed that the discipline of safety science should be constructed and improved with the concept of wide-ranging safety as the basis, the safety philosophy as the methodology, the scientific axiom "safety first" as the common view, and the people-oriented as the new concept of safety development, as well as based on the persisting in scientific concept of development and the exploration of the new theory of "safety-risk-culture". Emphasis is focused on the comparative study on the discipline of safety science and technology between in the newly-issued GB/T13745-2009 and in the old GB/T13745-1992. This paper thinks highly of the significance and the deep influence of the new system of safety science and technology in GB/T13745-2009. The construction of safety science and technology discipline begins to enter a new period and needs developing and innovating in practice and exploration. The safety science in China is sure to thrive.