Effect of 131I nuclide therapy operation mode correction on radiation safety risk

doi:10.16265/j.cnki.issn1003-3033.2024.08.1612

Abstract

Abstract:

To protect the occupational health and safety of ¹³¹I nuclear therapy workers and increase the utilization rate of ¹³¹I nuclear therapy, ¹³¹I nuclear therapy workplaces in 10 hospitals in Shenzhen were selected in this study. The iodine box filter membrane sampling method, combined with a low background high-purity germanium γ energy spectrometer and passive efficiency calibration software, was used to measure the ¹³¹I activity concentration in critical areas of nuclear medicine workplaces. The accumulated effective dose of occupational personnel was estimated, and then the radiation safety risk of occupational personnel was evaluated. Furthermore, the effect of the correction factor change of ¹³¹I nuclide treatment operation on the radiation safety risk of occupational personnel was analyzed. The results showed that when the correction factor of ¹³¹I (liquid) nuclide treatment operation mode was set to 10, the radiation safety risk was far below the standard limit for manufacturer delivery and automatic packaging in nuclear medicine workplaces. It was recommended that the correction factor of the operation model of ¹³¹I (liquid) radionuclide therapy be distinguished by the packaging system, with manual packaging set to 1 and manufacturer delivery and automatic packaging set to 10.

Key words: ¹³¹I nuclear therapy, operating mode, correction factor, radiation safety risk, nuclear medicine workplace, internal radiation

CLC Number:

X945

FENG Jiangping, ZHANG Jinfan, CHEN Feng, LIN Zehua, GUO Jianfeng, LIU Yong. Effect of ¹³¹I nuclide therapy operation mode correction on radiation safety risk[J]. China Safety Science Journal, 2024, 34(8): 231-237.

Figures/Tables 5

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References 21

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核医学工作场所	日均操作量/Bq	操作方式	操作人数	年操作时间/h
A医院	7.40×10⁸	厂家分装,确认药量后给药	1	100
B医院	2.59×10¹⁰	厂家分装,确认药量后给药	5	200
C医院	2.59×10¹⁰	自动分装、给药	4	200
D医院	7.40×10⁸	厂家分装,确认药量后给药	2	100
E医院	7.40×10⁸	厂家分装,确认药量后给药	2	100
F医院	1.85×10⁹	厂家分装,确认药量后给药	6	100
G医院	7.40×10⁸	厂家分装,确认药量后给药	3	100
H医院	5.55×10⁸	厂家分装,确认药量后给药	2	100
I医院	7.4×10⁸	厂家分装,确认药量后给药	3	100
J医院	1.85×10⁹	厂家分装,确认药量后给药	3	100

工作场所	检测点位	检测结果/ (Bq·m^-3)		工作场所	检测点位	检测结果/ (Bq·m^-3)
A医院	给药室	0.32		F医院	给药室	38.1
	给药室	0.01		G医院	给药室	43.50
	候诊走廊	0.01		G医院	注射室	未检出
B医院	碘质控室	0.87		H医院	投药注射室	未检出
B医院	碘病房走廊	9.62		H医院	投药注射室	0.378
C医院	自动分装柜旁	61.81		I医院	二楼准备室	未检出
D医院	分装柜旁	未检出		J医院	注射窗	未检出
E医院	注射室	未检出			服药窗	20.30
E医院	SPECT 机房		未检出		服药窗	20.30

工作场所	检测结果/ (Bq· m^-3)	计算参数			人均待积有效剂量/ (mSv·a^-1)
工作场所	检测结果/ (Bq· m^-3)	年操作时间/h	人呼吸率/ (m³· h^-1)	剂量系数/ (Sv· Bq^-1)	人均待积有效剂量/ (mSv·a^-1)
A医院	0.32	100	0.83	2×10^-8	5.31×10^-4
B医院	0.87	200	0.83	2×10^-8	4.78×10^-4
C医院	61.81	200	0.83	2×10^-8	5.13×10^-2
F医院	38.1	100	0.83	2×10^-8	1×10^-2
G医院	43.5	100	0.83	2×10^-8	1.4×10^-2
H医院	0.378	100	0.83	2×10^-8	3.14×10^-4
J医院	20.3	100	0.83	2×10^-8	1.12×10^-2

工作场所	¹³¹I日等效最大操作量/Bq	工作场所日等效最大操作量/Bq	¹³¹I 占比/%
A医院	7.40×10⁷	7.77×10⁷	95.24
B医院	2.59×10⁹	2.60×10⁹	99.62
C医院	1.85×10⁹	1.85×10⁹	99.80
D医院	7.40×10⁷	9.99×10⁷	74.07
E医院	7.40×10⁷	7.59×10⁷	97.50
F医院	1.85×10⁸	1.99×10⁸	92.96
G医院	7.40×10⁷	8.88×10⁷	83.33
H医院	5.55×10⁷	5.99×10⁷	92.65
I医院	7.40×10⁷	1.04×10⁸	71.15
J医院	1.85×10⁸	1.89×10⁸	97.88
合计	5.24×10⁹	5.35×10⁹	97.90

活动类型	核素及状态	操作方式界定	操作方式修正因子
核素治疗	手动分装¹³¹I(液体)	简单操作	1
核素治疗	自动分装、厂家配送¹³¹I(液体)	很简单操作	10

Effect of ¹³¹I nuclide therapy operation mode correction on radiation safety risk

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