Abstract: In order to get more information concerning flame propagation and pressure in pipes of interconnected vessels and thereby to provide valuable information for safety protection and design,the flame propagation through pipes in large interconnected vessels produced by maize starch dust explosion Was investigated by experimental and numerical approaches.The experimental result shows that dust concentration has an important influence on the flame propagation behavior;under a very low dust concentration,the flame can still propagate in pipes with acceleration and produce a very violent explosion eventually.In simulation,the Eulerian-Lagrangian approach was used as a numerical model to simulate the phenomenon of two-phase flows,and a two-dimensional simulation on the above experiment was conducted by solving the conservation equations of unsteady turbulent two-phase reacting flows.The simulation results are in good accord with the experimental ones,which demonstrates that the numerical model can be well applied in the study of flame propagation caused by dust explosion.