Abstract: Based on the analysis of local coal mine work safety situation, the need to strengthen government regulation is discussed. It is pointed out that the failure of government regulation is the deep-seated cause for coal mine safety accidents. Based on the "economic man" hypothesis of public choice, the root causes for the failure of government regulation are analyzed from the game angle of the local coal mine supervision involving central government, local government, coal companies, mine workers and other multi-stakeholder. According to the facts of local government regulation of coal mine safety, the idea to build a multi-stakeholder government regulation system and its operating mechanism and specific routing is proposed. This is helpful to improve the executing ability of government regulation and reduce local coal mine accidents.