Abstract: In order to promote prediction of the hazardousness of a given chemical rapidly, the development of chemicals hazardousness prediction technology in the United States was studied in terms of chemical policy impact, prediction models and tools, and the gap in chemicals hazardousness prediction technology in China was discussed too. The results show that chemicals hazardousness data bases are the foundation of prediction technology, that building prediction models according to chemical hazard categories and characteristics of biological species to be evaluated, improving relevant regulations and standards of chemical prediction technology in combination with national chemical safety supervision requirements, and creating ways and means of facilitating public access to the data and prediction tools are important methods for promoting the development of chemicals hazardousness prediction technology in China.

Key words: chemicals, ecotoxicology, human health impacts, physicochemical properties, prediction technology