Abstract: In order to reduce the casualties and property losses caused by the traffic accidents on expressway and improve the rescue efficiency of command and dispatch center,the applicability of traffic rescue resource dispatch method is studied.Based on the mathematical characteristics.the allocation in the rescue depots and the rescuing implementation of the traffic accidents,the applicable conditions of the Hungarian method,the direct cost-based and opportunity cost-based method are proposed.Combined with the existing dispatch mode in the command and dispatch center,the dispatch rules of traffic rescue resource are made.By taking the expressway network on areas around Nanjing city as an instance.the proper traffic rescue resource dispatch methods are selected according to the applicable conditions and the dispatch decisions are made according to the dispatch rules.The results show that this study can provide a theoretical basis and proper method for the command and dispatch center to make a high efficient dispatching of the traffic rescue resource.