Abstract: The training goal for high-quality professionals of safety engineering specialty is studied and presented, which includes one concept, two knowledge frameworks, three learnings, four unities, five abilities and six consciousnesses. Through exploring into the training program for professionals, teaching process, engineering-oriented skill training and safety practice, a training mode for high-quality professionals of safety engineering specialty forms, which focuses on four aspects that are humanity quality and self-improvement, systems security ideas and project methods forming, chemical safety engineering and technology training, independent study and open practice. This mode shows clearly what to do, how to do and where to do for talent training. At the same time the mode was carried out in the training of safety engineering specialty's students at Jiangsu Polytechnic University from 2004 to 2009. The result shows that students' knowledge base, engineering practical ability, innovation spirit and ability were effectively trained and their integrated ability was formed to satisfy social needs.